mutational status of the brca genes Search Results


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Previously Published Breast and Ovarian Cancer Risks Associated with Mutations in BRCA1 and <t> BRCA2 </t>
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Previously Published Breast and Ovarian Cancer Risks Associated with Mutations in BRCA1 and <t> BRCA2 </t>
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Previously Published Breast and Ovarian Cancer Risks Associated with Mutations in BRCA1 and <t> BRCA2 </t>
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<t> BRCA </t> Test Results.
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Demographics of pancreatic cancer patients who underwent <t> BRCA1 </t> gene sequence analysis
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Demographics of pancreatic cancer patients who underwent <t> BRCA1 </t> gene sequence analysis
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Image Search Results


Previously Published Breast and Ovarian Cancer Risks Associated with Mutations in BRCA1 and  BRCA2

Journal:

Article Title: Average Risks of Breast and Ovarian Cancer Associated with BRCA1 or BRCA2 Mutations Detected in Case Series Unselected for Family History: A Combined Analysis of 22 Studies

doi:

Figure Lengend Snippet: Previously Published Breast and Ovarian Cancer Risks Associated with Mutations in BRCA1 and BRCA2

Article Snippet: Statistical Methods Kaplan-Meier estimation.— The cumulative probabilities of breast and ovarian cancer in mothers and sisters of BRCA1- and BRCA2- mutation carriers were estimated using the Kaplan-Meier product-limit method, using the program Stata (version 7).

Techniques:

Description of Studies Included in the Present Analysis

Journal:

Article Title: Average Risks of Breast and Ovarian Cancer Associated with BRCA1 or BRCA2 Mutations Detected in Case Series Unselected for Family History: A Combined Analysis of 22 Studies

doi:

Figure Lengend Snippet: Description of Studies Included in the Present Analysis

Article Snippet: Statistical Methods Kaplan-Meier estimation.— The cumulative probabilities of breast and ovarian cancer in mothers and sisters of BRCA1- and BRCA2- mutation carriers were estimated using the Kaplan-Meier product-limit method, using the program Stata (version 7).

Techniques: Sequencing

Kaplan-Meier cumulative breast (upper lines) and ovarian (lower lines) cancer probability in sisters (thick lines) and mothers (thin lines) of BRCA2-mutation–carrying index case patients.

Journal:

Article Title: Average Risks of Breast and Ovarian Cancer Associated with BRCA1 or BRCA2 Mutations Detected in Case Series Unselected for Family History: A Combined Analysis of 22 Studies

doi:

Figure Lengend Snippet: Kaplan-Meier cumulative breast (upper lines) and ovarian (lower lines) cancer probability in sisters (thick lines) and mothers (thin lines) of BRCA2-mutation–carrying index case patients.

Article Snippet: Statistical Methods Kaplan-Meier estimation.— The cumulative probabilities of breast and ovarian cancer in mothers and sisters of BRCA1- and BRCA2- mutation carriers were estimated using the Kaplan-Meier product-limit method, using the program Stata (version 7).

Techniques: Mutagenesis

Cumulative risk of breast (♦) and ovarian (▪) cancer in BRCA2-mutation carriers.

Journal:

Article Title: Average Risks of Breast and Ovarian Cancer Associated with BRCA1 or BRCA2 Mutations Detected in Case Series Unselected for Family History: A Combined Analysis of 22 Studies

doi:

Figure Lengend Snippet: Cumulative risk of breast (♦) and ovarian (▪) cancer in BRCA2-mutation carriers.

Article Snippet: Statistical Methods Kaplan-Meier estimation.— The cumulative probabilities of breast and ovarian cancer in mothers and sisters of BRCA1- and BRCA2- mutation carriers were estimated using the Kaplan-Meier product-limit method, using the program Stata (version 7).

Techniques: Mutagenesis

RRs for  Mutation Carriers,  as Compared to Baseline, for Models Allowing for Center, Type-of-Index-Case, and Year-of-Birth Effects [Note]

Journal:

Article Title: Average Risks of Breast and Ovarian Cancer Associated with BRCA1 or BRCA2 Mutations Detected in Case Series Unselected for Family History: A Combined Analysis of 22 Studies

doi:

Figure Lengend Snippet: RRs for Mutation Carriers, as Compared to Baseline, for Models Allowing for Center, Type-of-Index-Case, and Year-of-Birth Effects [Note]

Article Snippet: Statistical Methods Kaplan-Meier estimation.— The cumulative probabilities of breast and ovarian cancer in mothers and sisters of BRCA1- and BRCA2- mutation carriers were estimated using the Kaplan-Meier product-limit method, using the program Stata (version 7).

Techniques: Mutagenesis

 BRCA  Test Results.

Journal: PeerJ

Article Title: Dealing with the unexpected: consumer responses to direct-access BRCA mutation testing

doi: 10.7717/peerj.8

Figure Lengend Snippet: BRCA Test Results.

Article Snippet: At the conclusion of the interviews, the BRCA mutation status of each participant was verified from the 23andMe database.

Techniques: Mutagenesis

Sharing of  BRCA  Results.

Journal: PeerJ

Article Title: Dealing with the unexpected: consumer responses to direct-access BRCA mutation testing

doi: 10.7717/peerj.8

Figure Lengend Snippet: Sharing of BRCA Results.

Article Snippet: At the conclusion of the interviews, the BRCA mutation status of each participant was verified from the 23andMe database.

Techniques:

Taking Action After Positive  23andMe   BRCA  Result.

Journal: PeerJ

Article Title: Dealing with the unexpected: consumer responses to direct-access BRCA mutation testing

doi: 10.7717/peerj.8

Figure Lengend Snippet: Taking Action After Positive 23andMe BRCA Result.

Article Snippet: At the conclusion of the interviews, the BRCA mutation status of each participant was verified from the 23andMe database.

Techniques: Imaging

Demographics of pancreatic cancer patients who underwent  BRCA1  gene sequence analysis

Journal:

Article Title: Absence of germline BRCA1 mutations in Familial Pancreatic Cancer Patients

doi:

Figure Lengend Snippet: Demographics of pancreatic cancer patients who underwent BRCA1 gene sequence analysis

Article Snippet: Data Analysis Prevalence and 95% confidence intervals of BRCA1 mutations, as well as analysis of pathological and family history data, was performed using STATA v9.0.

Techniques: Sequencing, Biomarker Discovery